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Taking Your CRESTOR

How and when to take CRESTOR

It is important to always take CRESTOR® (rosuvastatin calcium) exactly as prescribed by your doctor. Do not change your dose or stop CRESTOR without talking to your doctor, even if you are feeling well.

How should I take CRESTOR?

  • Take CRESTOR exactly as your doctor tells you to take it
  • Take CRESTOR, by mouth, 1 time each day. Swallow the tablet whole
  • CRESTOR can be taken at any time of day, with or without food
  • Do not change your dose or stop CRESTOR without talking to your doctor, even if you are feeling well
  • Your doctor may do blood tests to check your cholesterol levels before and during your treatment with CRESTOR. Your doctor may change your dose of CRESTOR if needed
  • Your doctor may start you on a cholesterol-lowering diet before giving you CRESTOR. Stay on this diet when you take CRESTOR
  • Wait at least 2 hours after taking CRESTOR to take an antacid that contains a combination of aluminum and magnesium hydroxide
  • If you miss a dose of CRESTOR, take it as soon as you remember. However, do not take 2 doses of CRESTOR within 12 hours of each other
  • If you take too much CRESTOR or overdose, call your doctor or go to the nearest hospital emergency room right away

Do not take CRESTOR if you:

  • are allergic to rosuvastatin calcium or any of the ingredients in CRESTOR
  • have liver problems
  • are pregnant or think you may be pregnant, or are planning to become pregnant. CRESTOR may harm your unborn baby. If you become pregnant, stop taking CRESTOR and call your doctor right away
  • are breastfeeding. CRESTOR can pass into your breast milk and may harm your baby. It is not known if CRESTOR passes into your breast milk. You and your doctor should decide the best way to feed your baby if you take CRESTOR
Learn more about side effects of CRESTOR

Note: It is important to take CRESTOR as prescribed and to discuss any health changes you experience while taking CRESTOR with your doctor. Do not use CRESTOR for a condition for which it was not prescribed. Do not give CRESTOR to other people, even if they have the same medical condition you have, as it may be harmful to them.

Important questions to ask your doctor

  • Will any of the medications I'm currently taking interact with CRESTOR?
  • Is there anything in my medical history that would cause a problem if I am taking CRESTOR?
  • Are there any medications (prescription or nonprescription) I should avoid taking with CRESTOR?
  • Can you tell me how to take CRESTOR?

Important Safety Information About CRESTOR Tablets


  • CRESTOR is not right for everyone. Do not take CRESTOR if you are nursing, pregnant or may become pregnant; have liver problems; or have had an allergic reaction to CRESTOR
  • Your doctor should do blood tests to check your liver before starting treatment and if you have symptoms of liver problems while taking CRESTOR
  • Call your doctor right away if you:
    • Have unexplained muscle pain or weakness, especially with fever
    • Have muscle problems that do not go away even after your doctor told you to stop taking CRESTOR
    • Feel unusually tired
    • Have loss of appetite, upper belly pain, dark urine, or yellowing of skin or eyes
  • These could be signs of rare but serious side effects
  • Elevated blood sugar levels have been reported with statins, including CRESTOR
  • Side effects: The most common side effects may include headache, muscle aches, abdominal pain, weakness, and nausea. Memory loss and confusion have also been reported with statins, including CRESTOR
  • Tell your doctor and pharmacist about other medicines you are taking

Talk to your doctor about prescription CRESTOR.

Approved Uses for CRESTOR

When diet and exercise alone aren't enough to lower cholesterol, adding CRESTOR can help.

In adults, CRESTOR is prescribed along with diet to lower high cholesterol and to slow plaque buildup in arteries as part of a treatment plan to lower cholesterol to goal.

Prescribing Information with Patient Information  (PDF - 152k) 


You are encouraged to report negative side effects of prescription drugs to the FDA. Visit or call 1-800-FDA-1088.

FlagThis site is intended for US consumers only.

The information on this Web site should not take the place of talking with your doctor or health care professional. If you have any questions about your condition, or if you would like more information about CRESTOR, talk to your doctor or pharmacist. Only you and your health care professional can decide if CRESTOR is right for you.