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Crestor® (rosuvastatin calcium)



 
Reducing the Risk of Heart Attack and Stroke

CRESTOR is FDA approved to reduce the risk of heart attack and stroke in individuals without known heart disease but at increased risk, specifically in women 60 years and older and men 50 years and older who have elevated (glossary term)hsCRP and at least one other risk factor. These other risk factors can include (glossary term)high blood pressure , smoking, low (video)HDL (good) cholesterol, and a family history of early heart disease.

You may have heard about hsCRP, which stands for high sensitivity C-Reactive Protein. This protein is produced by your body to indicate inflammation or infection. Elevated levels of hsCRP in the blood have been linked with increased risk of heart disease and stroke.

In a large (glossary term)clinical trial of more than 17,000 people, CRESTOR was proven to reduce the risk of heart attack and stroke in men 50 years and older and women 60 years and older with an elevated hsCRP level (2 mg/L or higher) plus at least one additional risk factor (such as high blood pressure, low HDL "good" cholesterol, smoking, or family history of early heart disease).

Ask your doctor if you should have your hsCRP level tested. It can be measured with a simple blood test. If you are tested and your doctor determines that the level is high, he or she may consider this information along with your other risk factors and prescribe CRESTOR to reduce your risk of heart attack and stroke.

Learn if you may be at increased risk for heart attack or stroke. Read the risk factor information below, then talk to your doctor to learn specific steps you can take to reduce your risk of heart attack or stroke.

Could CRESTOR help reduce your risk
of heart attack and stroke?
Are you:
  • A woman 60 or older
  • A man 50 or older
with:
  • Elevated levels of hsCRP
and have at least one additional risk factor for heart attack and stroke such as:
  • High blood pressure
  • Smoking
  • Low HDL-C
  • Family history of early heart disease

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Send these risk factors to anyone you know who might be at increased risk for heart attack or stroke. Then they can talk to their doctor to see if CRESTOR is right for them.


CRESTOR may not be right for everyone. It's always important to know the possible risks of taking a cholesterol medication.



Please see full Prescribing Information for CRESTOR
http://www.astrazeneca-us.com/cgi-bin/az_pi.cgi?product=crestor&country=us&popup=no

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.FDA.gov/medwatch or call 1-800-FDA-1088.

CRESTOR is licensed from SHIONOGI & CO, LTD, Osaka, Japan.



hsCRP
hsCRP is a sign of inflammation and, when elevated, can be associated with an increased risk of cardiovascular events (for example, heart attack or stroke). hsCRP is measured by a simple blood test.
High blood pressure
When the pressure at which blood is pumped through the arteries by the heart is above an average range, it is called high blood pressure, or hypertension. Blood pressure is recorded as two numbers—the systolic pressure (as the heart beats) over the diastolic pressure (as the heart relaxes).
Clinical trial
Clinical trials are research studies conducted to evaluate the safety and effectiveness of medications. In a typical clinical trial, groups of patients are asked to take a certain medication. This may be a specific dose of an existing medication, a dose of a new medication, or a placebo (sugar pill). Researchers then gather data over time and analyze the results.