Clinical Trial Results
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Often doctors will use the results of 
to help them evaluate different medications.
The interactive tool below shows how 
was lowered in a clinical trial results, known as (comparison of the efficacy and safety of rosuvastatin versus simvastatin, atorvastatin, and pravastatin across doses).
This tool is not meant to show which cholesterol medication is right for you. Ask your doctor about clinical trial results involving CRESTOR® (rosuvastatin calcium) and what the results mean. Then, together, you can decide what action to take.
Important Safety Information about CRESTOR
- CRESTOR is not right for everyone, including anyone who has previously had an allergic reaction to CRESTOR, anyone with liver problems, or women who are nursing, pregnant, or who may become pregnant
- Your doctor should do blood tests before and during treatment with CRESTOR to monitor your liver function
- Unexplained muscle pain or weakness could be a sign of a rare but serious side effect and should be reported to your doctor right away
- Elevated blood sugar levels have been reported with statins, including CRESTOR
- The most common side effects are headache, muscle aches, abdominal pain, weakness, and nausea
- The dose range for CRESTOR is 5 to 40 mg once daily. The usual starting dose is 10-20 mg
- CRESTOR 40 mg should be used only for those patients not achieving their LDL-C goal with 20 mg
About the STELLAR Trial
STELLAR was a 6-week clinical trial results involving 2,240 patients who had high cholesterol at the beginning of the trial. Patients were given different dosages of one of the following statin medications: CRESTOR® (rosuvastatin calcium), Lipitor® (atorvastatin), Zocor® (simvastatin), and Pravachol® (pravastatin). The researchers then compared the changes in the patients' LDL-C between the different drugs and dosages. In the STELLAR trial, the occurrence of adverse events was similar between treatment groups. The most common adverse events were pain, sore throat, muscle ache, and headache.
More Facts to Consider About CRESTOR
When diet and exercise alone aren't enough to lower your cholesterol, it's important to discuss your treatment options with your doctor and choose a medication that's right for you.
- There is no approved generic form of CRESTOR
- CRESTOR lowers LDL (bad) cholesterol and raises HDL (good) cholesterol
- CRESTOR is proven to slow the progression of atherosclerosis, the buildup of plaque in the arteries over time
- CRESTOR is FDA-approved to reduce the risk of heart attack and stroke in people without known heart disease but at increased risk based on age (women 60 years and older, men 50 years and older), elevated blood levels of ,§ plus at least one additional risk factor‖
§ hsCRP is a sign of inflammation that can be associated with increased risk of CV events.
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Additional risk factors can include high blood pressure, low HDL-C, smoking, or family history of early heart disease.
